Three categories. One private door.
Sildenafil, tadalafil daily, or compounded troche.
SSRIs (paroxetine), topical lidocaine/prilocaine.
Bloodwork → testosterone or clomiphene protocols.
Three molecules. Pick the rhythm that matches your life.
All three are well-studied, generic, and dispensed by US pharmacies. Cost differences are real but small; the lifestyle differences are larger.
Most prescribed PDE5 inhibitor in the world. Predictable, well-studied, slightly tighter window.
Daily microdose so spontaneity returns. Also helps BPH urinary symptoms.
Dissolved under the tongue. Bypasses gut. Faster, longer, and dispensed by a US-licensed compounding pharmacy.
From first message to box on your porch.
Median member receives a signed prescription in under an hour and the package within 4 days. Here's what happens at each gate.
Chat with Clyne Concierge in plain language. No medical jargon required.
Demographics, history, current meds, lifestyle, and the symptom timeline.
Last BP, height, weight. Drivers license uploaded for state of practice.
On-staff doctor opens the AI summary, intake, and risk flags. Approves, modifies, or asks for follow-up.
Sent to a US-licensed pharmacy in your state. Lot, NDC, and expiration logged in your dashboard.
Generic 7×7 box, no pharmacy branding. Tracking and delivery confirmation in-app.
If we suspect low T, we run the panel.
An at-home finger-prick or local lab draw. Eight markers tell us whether you need a hormone protocol, a cardiology referral, or just better sleep.
Intake without a clipboard.
A structured chat replaces the form. Clyne Concierge asks about medical history, current medications, and what you've already tried. Your physician reviews your case (typically same business day) and either approves a starting protocol or asks a clarifying question.
First-line review.
Your physician reviews medications that commonly contribute to ED (SSRIs, beta-blockers, certain antihypertensives), comorbidities (diabetes, hypertension, dyslipidemia), and lifestyle factors before settling on a PDE5 inhibitor. Goldstein NEJM 1998 established the first-line role for sildenafil; Brock J Urol 2002 and Porst Eur Urol 2006 established the daily-tadalafil pathway.
Discreet shipping arrives.
Unmarked box, addressed to the member, with the pharmacy invoice on the inside. Standard delivery to most US addresses within 3–5 business days of physician approval.
Steady-state response.
Daily tadalafil reaches steady state around day 5–9 (5 mg/day). PRN sildenafil works within ~30–60 minutes. Trial baselines: IIEF-EF improvements demonstrated in the cited NEJM and J Urol trials. Individual results vary.
Comorbidity check-in.
Your physician may order labs (testosterone, HbA1c, lipid panel) if the intake flags concerns. The first-month review covers tolerability and whether any contributing medications need a separate conversation with the prescribing clinician.
Care-team coordination.
If a contributing medication needs adjustment (e.g. SSRI), your Clyne physician coordinates with the prescribing clinician rather than handling it unilaterally. The PDE5 dose is typically held steady through any taper.
Quarterly review.
Your physician reviews how the protocol is working, considers dose reduction if response is sustained, and sets the cadence for the next quarter. The Porst 2006 trial showed sustained tadalafil benefit through 12 weeks of daily dosing.
Three plans. No surge.
One subscription. Cancel any time. Labs, follow-ups, and Clyne Concierge included.
- Sildenafil 50 mg or tadalafil 20 mg
- Generic. US-pharmacy compounded.
- Free reschedule of doses
- Clyne Concierge follow-ups included
- 30 daily tablets shipped each month
- Ongoing physician oversight
- Free dose adjustment
- Drug-interaction screen against your med list
- 8-marker hormone panel (ordered by your physician)
- Endocrinology + urology dual review
- Compounded options on request
- TRT eligibility assessed if indicated
Real doctors. Not a chatbot in a lab coat.
Every prescription is signed by a US-licensed physician on staff. They review the AI summary, the intake, and the bloodwork — then make the call.
Your physician is US-licensed, board-certified, and reviews every case personally.
The studies behind the script. Cited.
We say no, often.
About 18% of sexual-wellness intakes get bounced. The reasons aren't a moral judgment — they're safety arithmetic.
The questions you actually want to ask. Without judgment.
Available treatments in this category. Pick a path.
- SEXUAL WELLNESS
Sildenafil Tablet
Read product page → - SEXUAL WELLNESS
Tadalafil Tablet
Read product page → - SEXUAL WELLNESS
ED 3-in-1 Troche
Read product page → - SEXUAL WELLNESS
Clyne Desire RDT
Read product page → - SEXUAL WELLNESS
ED 3-in-1 High-Dose Troche
Read product page → - SEXUAL WELLNESS
Dual PDE5 RDT
Read product page →
Still deciding? Ask the AI.
No signup. No gated form. Get a physician-reviewed answer in under a minute.